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What is collagen and why do use it?

It is the substance that holds the body together. Collagen forms a scaffold to provide strength and structure.
Endogenous collagen is natural collagen synthesized by the body. Exogenous collagen is synthetic. It comes from an external source such as supplements. Endogenous collagen has a number of important functions.
Exogenous collagen is used for medical and cosmetic purposes, including the repair of body tissues.

Some facts about collagen

Here are some key points about collagen.
Collagen is found in the body, skin, bones and connective tissues.
Some types of collagen fibrils are stronger than steel.
Collagen production decreases with age, exposure to factors such as smoking and sunlight.
It can be used in collagen dressings to attract new skin cells to wound areas.

What is collagen?

Collagen is a hard, insoluble and fibrous protein that makes up one-third of the protein in the human body. In most collagen, the molecules come together to form long, thin fibrils.
These act as supporting structures and bind cells together. They give strength and elasticity to the skin.
There are at least 16 different types of collagen, but 80 to 90 percent of them belong to types 1, 2, and 3. These different types have different structures and functions.
Collagens in the human body are strong and flexible.

What does collagen do?

Collagen is secreted by various cells, but mainly by connective tissue cells.
It is found in the extracellular matrix. This is a complex network of macromolecules that determines the physical properties of body tissues. A macromolecule is a molecule containing a large number of atoms.
In the dermis, or middle layer of the skin, collagen helps create a fibrous network of cells called fibroblasts on which new cells can grow. It also plays a role in replacing and regenerating dead skin cells.
Some collagen acts as a protective coating for sensitive organs in the body, such as the kidneys.
With age, the body produces less collagen. The structural integrity of the skin is reduced. Wrinkles form and the articular cartilage weakens.
Women experience a dramatic decrease in collagen synthesis after menopause.
By the age of 60, a significant decrease in collagen production is normal.

Collagen in the medical and cosmetic field

Collagen can be absorbed. This means it can be broken down, transformed and reabsorbed into the body.
Its wide variety of functions and natural occurrence make it clinically versatile and suitable for a variety of medicinal purposes.

Skin fillers

Collagen injections can improve the contours of the skin and fill in depressions.
Collagen-containing fillers can be used cosmetically to remove facial lines and wrinkles.
Collagen can fill relatively superficial volumes. Larger spaces are usually filled with substances such as oil, silicone or implants.

wound dressing

Collagen can help wounds heal by attracting new skin cells to the wound site. It promotes healing and provides a platform for new tissue growth.

skin rejuvenation

Many products containing collagen, including creams and powders, rejuvenate the skin by increasing collagen levels in the body.
Such treatments are not classified as drugs, so any claims about their effectiveness do not need to be scientifically proven. Caution is advised when using these products.

Preventing collagen loss

Laser therapy can help treat stretch marks as it can stimulate the growth of collagen, elastin, and melanin.
A healthy diet can help the body produce collagen.

Nutrients that can support collagen formation include:
Proline: In egg whites, meat, cheese, soy and cabbage.
Anthocyanidins: In blackberries, blueberries, cherries and raspberries.
Vitamin C: In oranges, strawberries, peppers and broccoli.
Copper: Found in shellfish, nuts, red meat and some drinking water.
Vitamin A: Found as beta-carotene in foods of animal origin and plant foods.

What harms collagen?

Some factors can lower the level of collagen in the body. Avoiding these factors can keep skin healthy for longer.

Sunlight: Ultraviolet rays in sunlight cause collagen to break down faster, damage collagen fibers, and abnormal elastin buildup.
UV rays in sunlight damage the collagen in the dermis and the skin is restructured incorrectly, resulting in wrinkles.
Autoimmune disorders: Some autoimmune disorders cause antibodies to target collagen.
Genetic changes can affect the extracellular matrix. The collagen produced may be lower, or it may be non-functional (mutated) collagen.The aging process causes collagen levels to deplete naturally over time. There is no way to prevent this. Tobacco, avoiding excessive sun exposure, following a healthy diet, exercise regimen help reduce visible aging and protect collagen. Keeps skin, bones, muscles and joints healthy for longer.


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